It has long been thought that the central nervous system is able to influence the progression of disease. Furthermore, there is now overwhelming evidence that the communication pathways are bidirectional. A variety of immune system peptides are now known to be capable of transmitting information from the immune system to the central nervous system. These immunotransmitters include interleukins, interferons and thymosine peptides which have the capability of modulating slow‐wave sleep as well as the release of neuro‐ and pituitary peptides. In (...) some instances, release of these peptides during early development may have long lasting, if not permanent effects upon the normal development of neuro‐endocrine circuits. Collectively these various brain mediated events appear to contribute in various and diverse ways to defense against pathogens. It is becoming more and more apparent that certain abnormalities within the immune system may be the consequence of a neurological abnormality. The converse is also true. (shrink)

Priming reflects the reactivation of processing routines that map strings of words onto semantic representations (and vice versa) without the mediation of syntactic structure, including the “flat structure” that Branigan & Pickering (B&P) propose. Key evidence for this claim comes from the possibility of priming relations involving subject-verb sequences, which are not syntactic constituents.

Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants’ locations, online activity, phone and text message usage, heart rate, sleep, physical activity, and more. Existing ethical frameworks for return of individual research results (IRRs) are inadequate to guide researchers for when, if, and how to return this unprecedented number of potentially sensitive results about each participant’s real-world behavior. To address this gap, we convened an interdisciplinary expert working group, supported by (...) a National Institute of Mental Health grant. Building on established guidelines and the emerging norm of returning results in participant-centered research, we present a novel framework specific to the ethical, legal, and social implications of returning IRRs in digital phenotyping research. Our framework offers researchers, clinicians, and Institutional Review Boards (IRBs) urgently needed guidance, and the principles developed here in the context of psychiatry will be readily adaptable to other therapeutic areas. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:156 BOOK REVIEWS human being with happiness" (p. 34). I would only add that happiness is the reward of any reader who gives this book the attention that it deserves. Center for Thomistic Studies Houston, Texas JOHN F. x. KNASAS Henry VIII and the Conforming Catholics. By PAUL O'GRADY. Collegeville, Minnesota: The Liturgical Press, 1990. Pp. 186. $11.95 (paper). The careers and writings of what this author has (...) called " Conforming Catholics " have been generally neglected by historians of the English Reformation, at least until recently. That is why it is even more remarkable that not only one, but two books should be published in 1990 on this subject. Glyn Redworth's life of Stephen Gardiner, bishop of Winchester (Jn Defense of the Church Catholic, London: Basil Blackwell) is primarily a historical and biographical account of this pivotal anti-papal Catholic, with particular emphasis on the period from 1540-1547. This book, while complete and well written, concentrated on the life of Bishop Gardiner almost to the exclusion of his writings, though some of these were mentioned in passing. Paul O'Grady's book suffers from almost the reverse of that problem. In his Introduction, he contends that " intellectual systems, once generated, have a logic of their own." His concentration on the " intellectual system " of anti-papal Catholicism at times overwhelms the historical considerations of the period, and he falls into at least the neglect of what Professor Geoffrey Elton calls " uncertainty as to what actually happened." Dates are plentiful in this consideration, to be sure, but the events selected are limited, and one gets the impression that there is quite a bit more to the story than the author is letting on. Quite a bit of familiarity with the period is assumed by the author on the part of the reader, and much that is quite germane to the topic and useful to following the text is relegated to footnotes. The great contribution of this study is that it raises a number of names to a higher profile, and highlights their writings. Gardiner, though relatively neglected (at least until recently), is one of the few names that surface about which a biography has been written. There has been a significant amount of groundwork done for this book, and merely the listing of titles by these authors is a valuable contribution. But there are problems, some of which are hardly the fault of the author. O'Grady uses the term "Henrician Catholic" in a number of BOOK REVIEWS 157 places, which causes one to wonder, what was the Catholicism of Henry VIII himself? J. J. Scarisbrick, in his magisterial biography of the king, certainly goes over the evidence, and O'Grady adds nothing new. The sources are scanty, and one is forced at times to make a series of assumptions (based on Henry's choice of bishops and councilors, for example) about what Henry actually believed that eventually become a series of assumptions piled on top of other assumptions. Noticeably and significantly absent from the consideration of Henry's management of his ecclesiastics is any attention to Henry's plan for the formation of a strong Tudor monarchy within England, the long standing work of Professor Elton. Foreign policy, another issue in the religious settlement of the period, is mentioned occasionally and briefly (here Professor Redworth's book more than makes up the difference). One cannot attempt to determine the king's theological positions in a vacuum, and although Henry VIII did (and still does) have some reputation as an " amateur theologian " in the period in question, there are few purely theological statements by that monarch. Theology, to all appearances, was just one lever used by Henry in erecting a strong modern state: the imposition of theological and liturgical uniformity was almost always a means to political uniformity, as the Prayer Book Revolts in Cornwall and the West showed in Edward's reign. Another problem arises in determining who, exactly, is an Henrician Catholic? It is fairly simple to differentiate this group from the Reformers -the controversies over the Sacrament and justification by faith do this clearly. But how can they he separated from the Roman Catholics? O'Grady... (shrink)

The chapter begins with a brief preliminary investigation of the nature and role of theory in psychotherapy in general. Then, it introduces Gestalt therapy in an institutional and historical context. The distinctive theoretical tenets of Gestalt psychotherapy are outlined next. The chapter looks at some of the philosophical underpinnings of this theory and notes how such underpinnings tend toward subjectivism and an anti‐theory stance. It also suggests some alternative underpinnings, which could lead to a more integrated outlook on the relation (...) of theory to practice and a resolution of the objectivity‐subjectivity tension. (shrink)

The cerebral distinctness of the linguistic and mathematical faculties does not entail their functional independence. Approaches to language that posit a common foundation for the two make claims about design features, not location, and are thus not affected by the finding that one ability can be spared by a neurological accident that compromises the other.

An accessible guide to philosophy, presenting a collection of 70 essays covering the major themes, theories and arguments of the most prominent thinkers of ancient Greece.

The critical commentaries that take up the work of Julia Kristeva all too often disregard the 'religious content' that is central to her oeuvre from the 1980s to the present. Topics such as maternity, abjection, love and melancholia have been covered extensively by readers of Kristeva, yet most neglect to forge a connection between Kristevan theory and her religious, primarily Catholic, forays and examples, choosing to view these theologically inspired illustrations as merely incidental to her theory. And those readers who (...) have addressed the religious component of Kristeva's work, most notably feminist commentators, have dismissed it, labelling it with such terms as 'regressive', 'sentimental' and 'nostalgic' or 'troubling'. This paper argues that much of the confusion concerning Kristeva's relationship to feminism and the all too common attacks of essentialism, sexism and conservatism that are made against her, arise directly from the exclusion of her writings on theology and religion. What has ensued in the secondary source material has been a proliferation of false information concerning both Kristeva herself and her theoretical work, and a number of misplaced criticisms have followed. By truncating the religious dimen sion of Kristeva's philosophy, feminist readers have risked misunderstanding the import and scope of her entire project. Through a detailed examination of Kristeva's use of the image of 'Saint Barbara' in her theoretical, fictive and autobiographical works, this essay establishes that there is a direct connection between her core theoretical assertions and her views on religion. 'But we are, I know not how, double within ourselves'. 1. (shrink)

"...there is nothing elementary about O'Grady's primer. She pulls off the feat of writing a reliable and accessible introduction to modern philosophy that is also a meaningful contribution to the subject." - London Times Literary Supplement From Descartes' famous line 'I think therefore I am' to Kant's fascinating discussions of morality, the thinkers of the Enlightenment have helped to shape the modern world. Addressing such important subjects as the foundations of knowledge and the role of ethics, the theories of (...) these philosophers continue to have great relevance to our lives. Ranging across Enlightenment thinking from Berkeley to Rousseau, Enlightenment Philosophy in a Nutshell explains important ideas such as Locke's ideas of primary and secondary qualities, Kant's moral rationalism, and Hume's inductive reasoning. Filled with helpful diagrams and simple summaries of complex theories, this essential introduction brings the great ideas of the past to everyone. (shrink)

Paul O'Grady clearly distinguishes five main kinds: relativism about truth, relativism about logic, ontological relativism, epistemological relativism, and, finally, relativism about rationality. In each case he shows what makes a position relativist and how it differs from a sceptical or pluralist position. He ends by presenting a thoroughly integrated position that rejects some forms while defending others. The book includes discussion of recent work by Putnam, Devitt, Searle, Priest, and Quine and offers a succinct survey of contemporary debates. This (...) lively discussion of the issue will be welcome reading for all those involved in philosophical inquiry. (shrink)